Semaglutide

Mu Kuboza 2017, Ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA) cyemeje urutonde rw’inshinge ya peptide ya Smeglugan mu kugenzura indyo y’imyitozo ngororamubiri no gukora imyitozo ngororamubiri hagamijwe kunoza igenzura ry’amaraso glucose y’abarwayi ba diyabete yo mu bwoko bwa 2.Byongeye kandi, Novo na Nord banateje imbere ubwoko bwa dosiye yo mu kanwa Rybelsus ya Smeglugin, kandi byemejwe bwa mbere na FDA muri Nzeri 2019. Uyu kandi niwo muti wa mbere wemewe ku isi GLP-1.diyabete.Mubyukuri, Smeglugin numuti wa hypoglycemic, ariko kubera ko imiti nka peptide ya Smeglugin ishobora kugabanya igifu ubusa kandi ikagabanya ubushake bwo kurya, bizagabanya ibiro.

Urebye ibi, muri kamena 2021, FDA yemeye kumugaragaro gucunga ibiro birebire birebire byumubyibuho ukabije cyangwa abantu bakuru bafite ibiro byinshi.Abantu basabwa ni: abarwayi boroheje bafite BMI kg30 kg / m2;na BMI> 27 kg / m2 hanyuma uhuze byibuze ikibazo kimwe cy'umubyibuho ukabije, nka hypertension, diyabete yo mu bwoko bwa 2, cyangwa lipide idasanzwe y'amaraso.Nibyemejwe kandi ko ibishushanyo mbonera byashyinguwe kuri Smeglugin kumuhanda w "imiti yo kugabanya ibiro".

Muri Mata 2021, Smegugan yemerewe mu Bushinwa kugenzura isukari mu maraso ku barwayi ba diyabete yo mu bwoko bwa 2 (T2DM).Nubwo kwerekana ibiro byerekana ibiro bitemewe mu Bushinwa, icyifuzo cyo kugabanya ibiro mu gihugu ntigishobora kubera mu Bushinwa.Byongeye kandi, insanganyamatsiko nyamukuru y "kunanuka no kunanuka", mu gice cya kabiri cya 2022, peptide ya Smeglugin "ntabwo yemeye" mu rwego rwo kugabanya ibiro., Iyo imaze kuba kuri e-bucuruzi nyinshi, yahagaritse kugura, kandi yigeze kuba igiciro cyinshi "hanze yumwami", ibyo bikaba byaratumye habaho ibibazo byumusaruro n’ibicuruzwa.Nyakanga muri Nuo na Nord muri Nyakanga umwaka ushize bavuze ko kongera gutanga ibiyobyabwenge bizahagarika itangwa ry’amasoko atari ibitaro.

Icyamamare cya peptide ya Smegugu nacyo cyemejwe uhereye ku makuru y’imari ya Nuo na Nord.Nk’uko ibisubizo 2022 biherutse gutangazwa na Nuo na Nord bibitangaza, amafaranga yinjiza buri mwaka mu bucuruzi bwa GLP-1 ya Nuo na Nord yari miliyari 83.371 Dan Ying Crown (ahwanye na miliyari 81,6 z'amayero), yiyongereyeho 56% umwaka ushize.Muri byo, Smeglugin yagurishijwe yari miliyari 59.75 Dan Ying Crown (ahwanye na miliyari 58.5 yuan), yiyongeraho 77% umwaka -wumwaka.Imikorere yo kugurisha ibicuruzwa bya GLP-1 mubijyanye no kuvura diyabete yo mu bwoko bwa 2 mu Bushinwa yiyongereyeho 102% muri Dan Ying Krone.

Birumvikana ko iturika rya Smeglugin murwego rwo kugabanya ibiro bifitanye isano rya hafi ningaruka zaryo zikomeye."Igihe kirageze cyo kurya, kunywa no kunywa, gufata ibiro 5, gutakaza ibiro 30 muri Mutarama" n'ibindi.Byongeye kandi, "kuryama neza" birashobora kuba byoroshye, bikurura amaso atabarika kuri peptide ya Smegtu, yahoze yitwa "imiti yo kugabanya ibiro".Icyakora, bamwe mu bavuzi bavuze ko peptide ya Simei Gulu ifite ibice birenga 2/3 by’igurishwa ry’imbere mu Bushinwa kugira ngo bigabanye ibiro, atari diyabete.Ku ruhande rumwe Kubijyanye na peptide ya Smeglugan nkumuti wandikirwa, hari akaga kihishe mumutekano wibiyobyabwenge byindwara.

Birakwiye ko tumenya ko imyanzuro yubushakashatsi bwakozwe murugo nk'ibi bituruka ku barwayi bafite umubyibuho ukabije.Kubantu bafite ibinure bike cyangwa nuburemere busanzwe (BM <27kg / m2), inyungu nibishobora kubaho ntibiramenyekana.Byongeye kandi, usibye reaction ya hypoglycemia ari imiti ya hypogenalique iboneka mu miti ya hypoglycemic, reaction ya gastrointestinal iragaragara, kandi indwara yo kugira isesemi, impatwe, kuruka no gucibwamo ni hejuru ya 82.8%.7%.Icy'ingenzi ni uko Smeglugin itemewe kubera ibimenyetso byerekana ibiro mu Bushinwa.Ikibazo cyimiyoboro yimiti no gukoresha ibiyobyabwenge abantu nkabo birakwiye kwitabwaho.