166108-71-0 Fmoc-AEEA-OH

166108-71-0 Fmoc-AEEA-OH ni umuhuza wa ADC uhuza ikoreshwa muguhuza antibody-ibiyobyabwenge (ADCs).Fmoc-8-amino-3,6-dioxaoctanoic aside nayo ni PEG ishingiye kuri PROTAC ishobora gukoreshwa muguhuza PROTACs.

166108-71-0 Fmoc-AEEA-OH nayo irashobora kuba imwe mungingo ya semaglutide.

Ingaruka nyamukuru ya semaglutide ni ukuvura diyabete yo mu bwoko bwa 2 mugabanya urugero rwa glucose.Yigana imisemburo ya insuline imeze nka peptide-1, itera imisemburo ya insuline kandi ikabuza kurekura glucagon, bityo bikagabanya urugero rwa glucose mu maraso.Semaglutide ntabwo igira uruhare mu byago bya hypoglycaemia ibaho ugereranije nubuvuzi busanzwe bwa insuline kuko uburyo bwibikorwa biragoye kandi neza.Muguhindura uburinganire bwa insuline na glucagon, somalutide irashobora gufasha abantu barwaye diyabete yo mu bwoko bwa 2 kugenzura neza urugero rwisukari rwamaraso.

Usibye kugabanya urugero rwisukari yamaraso, semaglutide irashobora kandi kugabanya ibiro byumubiri.Ibi biterwa ningaruka zayo zo kurya.semaglutide itera ibikorwa byikigo gihagije muri hypothalamus, igabanya ubushake bwo kurya.Inyungu nyamukuru ya semaglutide kurenza iyindi miti igabanya ibiro nuko itakaza ibiro mugihe irwanya insuline no kurwanya isukari mu maraso.Ibi bituma aribwo buryo bwiza bwo kuvura abarwayi ba diyabete bafite umubyibuho ukabije.

Byongeye kandi, semaglutide itezimbere imikorere ya pancreatic kandi igabanya ibisubizo byumuriro muri selile pancreatic islet selile.Irinda ingirangingo zirwanya kwangirika kwatewe na diyabete kandi iteza imbere ingirabuzimafatizo.Ibi ni ingenzi cyane kubantu barwaye diyabete yo mu bwoko bwa 2, kuko kwangirika kwingirabuzimafatizo cyane bishobora gutera kunanirwa kwizinga.

Muri rusange, semaglutide ni imiti ikora neza kandi yizewe yo kuvura diyabete yo mu bwoko bwa 2.Ifasha abarwayi kugenzura neza diyabete yabo no kugabanya ingorane mu kugabanya urugero rwa glucose yamaraso, kugabanya ibiro byumubiri, kunoza imikorere yizinga, no kurinda ingirabuzimafatizo.Inyigisho z'ejo hazaza zizakomeza gushakisha ubushobozi bwa somatostatine mu kuvura izindi ndwara, nka NAFLD n'umubyibuho ukabije.