Fmoc-L-Gln (Trt) -Aib-OH

Ikoreshwa rya Fmoc-L-Gln (Trt) -Aib-OH iratandukanye kandi ifite agaciro gakomeye mubice bitandukanye.Dore gusenyuka kwingenzi kwingenzi:
Peptide Synthesis:
Fmoc-L-Gln (Trt) -Aib-OH ikora nkibice byingenzi byubaka muburyo bukomeye bwa peptide.Ihuriro ryihariye ryitsinda rya Fmoc na Trt ririnda umutekano no gukemuka, bigafasha guteranya neza iminyururu ya peptide.
Kwinjizamo aside amine idasanzwe ya Aib (α-aminoisobutyric aside) ituma hashyirwaho urutonde rwihariye hamwe nibikorwa bya biologiya.
Ubwubatsi bwa poroteyine no guhindura:
Iyi nkomoko irashobora gukoreshwa muguhuza cyangwa poroteyine zihinduranya hamwe na aside amine ikurikirana, bigafasha kwiga imiterere n'imikorere ya poroteyine.
Intangiriro ya Aib irashobora guhuza neza poroteyine nka stabilite, ibikorwa byimikorere, cyangwa imikoranire nizindi molekile.
Kuvumbura ibiyobyabwenge no gushushanya:
Peptide irimo Fmoc-L-Gln (Trt) -Aib-OH irashobora gupimwa kubushobozi bwabo bwo kuvura, bigatuma iba abakandida bafite agaciro muguteza imbere ibiyobyabwenge.
Urutonde rwihariye rwa aminide acide hamwe no kuba Aib irashobora kongera guhuza no guhitamo kuri molekile zigamije.
Ibinyabuzima n'ibikoresho byerekana amashusho:
Ibiranga umwihariko wa Fmoc-L-Gln (Trt) -Aib-OH ituma bikwiranye no gukora ibinyabuzima hamwe n’ibikoresho byerekana amashusho.
Iperereza rirashobora gukoreshwa mukwiga inzira yibinyabuzima, kumenya imikoranire ya molekile, cyangwa ubufasha mugupima hakiri kare indwara.
Ubushakashatsi n'intego z'uburezi:
Bitewe na synthesis yoroheje hamwe nibintu bihamye, Fmoc-L-Gln (Trt) -Aib-OH ikoreshwa kenshi mubushakashatsi bwibanze nubushakashatsi bwubumenyi bwibinyabuzima na chimie organic.
Ifasha abanyeshuri nabashakashatsi gusobanukirwa neza no kumenya amahame nubuhanga bwa synthesis ya peptide na protein yubuhanga.