Ubushinwa 294855-91-7 Pal-Glu (OSU) -OH Inganda nUruganda |Jiayinglai

294855-91-7 Pal-Glu (OSU) -OH

Ibisobanuro bigufi:

Kugaragara	Ifu yera-yera
MF	C25H42N2O7
MW	482.61
Isuku	98+

Ohereza imeri kuri twe

Ibicuruzwa birambuye

Imiterere yo gutwara abantu
Birashobora kuba mubushuhe busanzwe

Saba uburyo bwo kohereza
Mu kirere Ku butaka Ku nyanja

Imiterere y'ububiko:
Komeza ahantu hijimye, Inert ikirere, Ubushyuhe bwicyumba

ubuzima bwiza
Hafi yimyaka 2

Ibicuruzwa byibuze Qty ：
1kg （imishyikirano）

Icyemezo:COA, gushonga ingingo, Ibisobanuro byihariye [α]_D²⁰

Tuzohereza amakuru yose ushaka.Urashobora kubona amakuru mbere nkibisobanuro.

Kubicuruzwa byabigenewe, twohereza amakuru mashya nyuma yo gusohoka.

Synonyme

Liraglutidesidechain;

Pal-Glu (OSu) -OH;

Liraglutideintermediate;

(S) -5 - ((2,5-dioxopyrrolidin-1-yl) oxy) -5-oxo-2-palmitamidopentanoicacid;

(S) -5 - ((2,5-dioxopyrrolidin-1-yl) oxy) -2-palmitamidopentanoicacid;

(S) -5 - ((2.5 -1-pyrrolidinyl) ester;

Nα-Palmitoyl- (L) -glutamicacid-γ-succinimidyl-α-tert-butylester

Gupakira imbere

Bakunze gukoreshwa mugupakira ifu.Biterwa nibisabwa nabakiriya.Noneho, tubwire ibyo usaba mbere yo gupakira niba ufite ibyifuzo byihariye.

gupakira hanze

1kg kugeza 25kg Gupakira hanze biragoye.Kandi biragoye guca no kwangiza.Irashobora kurinda ibicuruzwa byawe neza.

Porogaramu

Pal-Glu (OSU) -OH, izwi kandi nk'urunigi rwa liraglutide, ni uruganda rukomeye rwa chimique hamwe ningingo nyinshi zikoreshwa mubice bitandukanye.

Ubwa mbere, mubijyanye nubuzima nubuvuzi, Pal-Glu (OSU) -OH ikoreshwa nkumunyururu wuruhande rwa glucagon imeze nka peptide-1 (GLP-1) reseptor agonist.GLP-1 reseptor agonist igira uruhare runini mubushakashatsi bwa diyabete yo mu bwoko bwa 2.Muguhuza imisemburo ya endogenous metabolike GLP-1, aba agoniste batera imisemburo ya insuline kandi ikabuza gusohora glucagon, bityo igafasha kugenzura urugero rwisukari rwamaraso.Kubera iyo mpamvu, Pal-Glu (OSU) -OH ifite agaciro gakomeye mugutezimbere imiti ya diyabete.

Icya kabiri, Pal-Glu (OSU) -OH nayo ikoreshwa nkibikoresho fatizo kumiti ya polypeptide ikora.Imiterere yihariye ya chimique ituma igira uruhare mukubaka inyubako za peptide hamwe nibikorwa byihariye byibinyabuzima, bitanga uburyo bushya bwo gutegura imiti niterambere.Iyi miti ya polypeptide ifite uburyo bushoboka bwo kuvura indwara zitandukanye.

Byongeye, Pal-Glu (OSU) -OH irashobora gukoreshwa mugutegura ibindi bikoresho bifite imirimo yihariye.Bitewe nitsinda ryayo rikora hamwe nuburyo bugaragara, ikora nkurwego rwingenzi muguhuza molekile zigoye, kurushaho kwagura ibikorwa byayo muri chimie, siyanse yubumenyi, nibindi bice bifitanye isano.

Kuki Duhitamo

1. Kubijyanye na MOQ: Turashobora kubihindura dukurikije ibyo usabwa.
2. Kubijyanye nicyitegererezo: Icyitegererezo gisaba amafaranga yicyitegererezo, gishobora kuba imizigo yo gukusanya cyangwa ushobora kutwishyura mbere.
3. Amahugurwa yububiko, arashobora gutegurwa ukurikije umubare wicyitegererezo.
4. Dutanga serivisi nziza.Itsinda ryo kugurisha inararibonye rimaze kugukorera.
5. Kubijyanye no kungurana ibitekerezo: Nyamuneka ohereza imeri cyangwa unyandikire kukworohereza.

Mbere: 2460751-66-8 Fmoc-L-Lys [C20-OtBu-Glu (OtBu) -AEEA-AEEA] -OH

Ibikurikira: 323587-47-9 (2S) -2-Amino-3- (tert-butoxy) propanamide hydrochloride

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