7536-55-2 Boc-L-Asn-OH

Boc-L-Asn-OH, izwi kandi nka BOC-L-Asparagine, ni inkomoko ya aside amine ikomoka hamwe nibisabwa bitandukanye.

Ubwa mbere, Boc-L-Asn-OH isanga ikoreshwa cyane mubinyabuzima no kuvumbura ibiyobyabwenge.Ikora nkigice cyingenzi muri synthesis ya peptide, ituma hubakwa iminyururu ya peptide nibikorwa byihariye byibinyabuzima.Bitewe nimiterere yihariye yimiti, Boc-L-Asn-OH irashobora kwitwara hamwe nandi acide amine cyangwa ibiyigize, biganisha ku kubyara imiti mishya cyangwa molekile ya bioaktike ifite imirimo itandukanye.

Icya kabiri, Boc-L-Asn-OH nayo ifite porogaramu mubinyabuzima na biologiya.Irashobora gukora nka aside amine irinda monomer, ikarinda amatsinda akora mubindi acide amine cyangwa iminyururu ya peptide kwirinda imiti itifuzwa mugihe cyo guhuza cyangwa kweza.Byongeye kandi, Boc-L-Asn-OH irashobora gukoreshwa muguhindura urubuga rwihariye mubuhanga bwa poroteyine, guhindura imiterere n'imikorere ya poroteyine.

Byongeye kandi, mubijyanye na tekiniki yumusaruro, Boc-L-Asn-OH irashobora guhuzwa binyuze mumiti yihariye.Mubisanzwe, itegurwa ukoresheje tert-butoxycarbonyl chloride (cyangwa azide) na L-asparagine nkibikoresho byo gutangira.Acylation reaction ikurikirwa na acide ikoresheje aside citricike hanyuma igasukurwa no kongera gukora.Ubu buryo bwo kubyaza umusaruro butuma imyiteguro minini ya Boc-L-Asn-OH, yujuje ibyifuzo byayo bitandukanye.