84000-07-7 Fmoc-LN-Me-Ala-OH

Peptide Synthesis: Fmoc-LN-Me-Ala-OH ikora nk'inyubako yubaka mugice cya peptide ikomeye.Itsinda rya Fmoc (9-fluorenylmethoxycarbonyl) nitsinda rikoreshwa cyane kurinda ryemerera kugenzura no guhuza ibintu mugihe cyo kurambura peptide.Imyitwarire ya LN-Me-Ala itangiza aside amine yihariye ifite imiti ihindura imiti ishobora gutera peptide hamwe nibikorwa bidasanzwe byibinyabuzima.

Ubushakashatsi bwibikorwa byibinyabuzima: Kuba hari itsinda rya N-methyl muri Fmoc-LN-Me-Ala-OH rihindura imiterere yibinyabuzima by ibisigisigi bya alanine, birashoboka ko bitanga bioactivities nshya kuri peptide zirimo.Kubwibyo, iyi nteruro irashobora gukoreshwa mugukora iperereza kumikorere yibinyabuzima, nka poroteyine-protein, imikoreshereze ya enzyme, cyangwa reseptor ihuza, muri vitro cyangwa muburyo bwa selile.

Gutegura ibiyobyabwenge niterambere: Peptide yungutse cyane mugushushanya ibiyobyabwenge kubera umwihariko wabyo hamwe na biocompatibilité.Kwinjiza aside amine yahinduwe nka Fmoc-LN-Me-Ala-OH irashobora kongera ituze, gukomera, cyangwa ibikorwa byibinyabuzima bya peptide, bigatuma batanga ikizere cyo gusaba imiti.Abashakashatsi barashobora gukoresha iyi nteruro kugirango basuzume ibiyobyabwenge bishobora kuyobora cyangwa guhindura imiti ya farumasi yibiyobyabwenge bishingiye kuri peptide.

Inyigisho zubaka kandi zihuza: Imiterere yihariye yimiti ya Fmoc-LN-Me-Ala-OH irashobora kandi gukoreshwa mubushakashatsi bwibinyabuzima byubatswe.Mu kwinjiza iyi aside ikomoka kuri aside amine muri peptide, abashakashatsi barashobora gukora ubushakashatsi ku kuntu ihinduka ry’uruhererekane rwa aside amine rigira ingaruka ku guhitamo, gutuza, n’imikoranire ya peptide hamwe n’ibindi binyabuzima.